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目的研究本市中老年男性部分睾酮缺乏(PADAM)和勃起功能障碍(ED)的发生情况及相关影响因素。方法282例46~69周岁男性,按年龄分为3组,采用国际勃起功能指数(IIEF-5)和PADAM症状评分表进行问卷调查,测定血清睾酮(T)、游离睾酮(FT)。数据用SPSS软件包处理。结果3个年龄组之间T均数无明显差异(P>0.05),而FT均数有非常显著性差异(P<0.005);ED、PADAM发病率有非常显著性差异(P<0.001,P<0.005);PADAM组ED发病率高于对照组(P<0.005)。结论中老年男性随着年龄的增长血清T变化不明显,FT下降明显,ED和PADAM发病率均明显升高,PADAM的发病率与FT下降关系密切,中老年男性ED的发病与年龄、内分泌关系密切。
Objective To study the occurrence and related factors of partial testosterone deficiency (PADAM) and erectile dysfunction (ED) in middle-aged and elderly men in this city. Methods A total of 282 males (46-69 years old) were divided into three groups according to their age. Serum testosterone (T) and free testosterone (FT) were measured by questionnaire according to the International Erectile Function Index (IIEF-5) and PADAM Syndrome Scale. Data is processed using SPSS software package. Results There was no significant difference in T-scores among the three age groups (P> 0.05), but there was a significant difference in mean FT between the two groups (P <0.005). The incidence of ED and PADAM was significantly different (P <0.001, P <0.005). The incidence of ED in PADAM group was higher than that in control group (P <0.005). Conclusions There is no obvious change of serum T in middle-aged and elderly men with the decrease of FT, the incidence of ED and PADAM, and the incidence of PADAM are closely related to the decline of FT. The incidence of ED in middle-aged and elderly men is related to age and endocrine close.