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作者采用快速饱和量奎宁治疗严重疟疾取得满意疗效。病人和方法 16例严重恶性疟疾成年患者,其中6例脑型疟疾,10例有高度原虫血症。男性6例,女性10例,平均年龄25.9岁。将奎宁盐7mg/kg(相当于主药5.83mg/kg)溶于60ml 生理盐水中,用驱动式注射泵于30分钟注入静脉内,其后4小时给予维持量(奎宁盐10mg/kg,相当于主药8.33mg/kg),并分别在输注前及负荷输注的30分钟内每5分钟1次和35、40、60、90分钟时测血压、脉搏,同时做心电监测,于0、5、15、20、25、30、35、40、60分钟时
The authors used rapid saturation of quinine to treat severe malaria and achieved satisfactory results. Patients and Methods Sixteen adult patients with severe falciparum malaria, including 6 cerebral malaria and 10 with parasitemia. 6 males and 10 females, with an average age of 25.9 years. Quinine salt, 7 mg / kg (corresponding to 5.83 mg / kg as the main drug) was dissolved in 60 ml of physiological saline and injected intravenously over 30 minutes using a drive-on syringe pump, followed by a maintenance dose of quinine salt of 10 mg / kg , Equivalent to the main drug 8.33mg / kg) and were measured before infusion and infusion within 30 minutes once every 5 minutes and 35,40,60,90 minutes when blood pressure, pulse, at the same time to do ECG monitoring At 0, 5, 15, 20, 25, 30, 35, 40, 60 minutes