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实验方法:将体重约200克的雄性SD大鼠全身麻醉后,剃尽腹部体毛,在腹部切除直径为3cm的圆形皮肤,经如下处理后分为6组:保持创面干燥,皮肤缺损部不作任何处理为Ⅰ组;使创面保湿,用Opsite Wound贴附皮肤缺损部为Ⅱ组;术后创面外涂紫云膏后再用Opsite Wound贴附为Ⅲ组;在术前2周及术后给大鼠口服皮质类固醇激素(2mg/kg/d),缺损部不作处理为类固醇治疗组即Ⅳ组;用Opsite Wound贴附皮肤缺损部为Ⅴ
Experimental method: Male SD rats weighing about 200 g were subjected to general anesthesia, abdominal body hairs were shaved, and 3 cm diameter circular skin was ablated on the abdomen. After the following treatments, they were divided into 6 groups: the wounds were kept dry, and the skin defects were not preserved. All treatments were group I; moisturizing the wounds, attaching the skin defect to the group II with Opsite Wound; applying the purple cloud ointment after the wound and attaching with the Opsite Wound to the group III; giving rats 2 weeks before surgery and after surgery Oral corticosteroids (2 mg/kg/d), no defects in the steroid treatment group IV; with the skin patch with Opsite Wound V