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本文首次报道人参皂甙Rh_2用于环磷酰胺诱发小鼠白细胞减少的影响.当给以人参皂甙Rh_2在lg/kg/日或2g/kg/日时,对CY100mg/kg所致的小鼠外周血液中白细胞减少有显著的升高作用.提示人参皂甙Rh_2可以拮抗化学治癌药物毒副作用.
This article first reported the effect of ginsenoside Rh 2 on leukopenia induced by cyclophosphamide in mice. When ginsenoside Rh 2 was given at lg/kg/day or 2g/kg/day, the peripheral blood of CY100mg/kg mice was induced. There was a significant increase in neutropenia. It was suggested that ginsenoside Rh_2 could antagonize the toxic and side effects of chemotherapy drugs.