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目的探讨胰岛素对妊娠期糖尿病孕妇妊娠结局及新生儿预后的影响。方法选取2014年9月-2015年12月在该院就诊的110例妊娠期糖尿病孕妇为研究对象,采用随机数字表法分为两组,每组各55例。观察组采用胰岛素控制血糖,对照组采用个体化饮食干预,对比两组母婴预后的情况。结果两组治疗后血糖均有所降低,观察组降低幅度明显高于对照组(P<0.05);观察组在羊水过多、胎膜早破、妊娠期高血压疾病以及产褥感染发生率均明显低于对照组(均P<0.05);观察组巨大儿、早产儿以及胎儿宫内窘迫发生率均明显低于对照组(均P<0.05),而两组低血糖发生率比较差异无统计学意义(P>0.05)。结论采用胰岛素控制孕妇血糖,对降低母体并发症、改善子代预后有积极的影响。
Objective To investigate the effect of insulin on pregnancy outcome and prognosis of gestational diabetes mellitus in pregnant women. Methods One hundred and ten pregnant women with gestational diabetes mellitus who were treated in our hospital from September 2014 to December 2015 were selected as study subjects and divided into two groups with 55 cases in each group. The observation group used insulin to control blood sugar, and the control group used individualized diet intervention to compare the prognosis of the two groups. Results The blood glucose of the two groups decreased after treatment, and the decrease rate of the observation group was significantly higher than that of the control group (P <0.05). The observation group had the highest rates of amniotic fluid, premature rupture of membranes, hypertensive disorder of pregnancy and incidence of puerperal infection (P <0.05). The incidence of macrosomia, premature infants and fetal distress in the observation group were significantly lower than those in the control group (all P <0.05), while the incidence of hypoglycemia in the two groups had no statistical difference Significance (P> 0.05). Conclusion The use of insulin to control blood glucose in pregnant women has a positive effect on reducing maternal complications and improving the prognosis of offspring.