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应用阴道超声观测15例不孕妇女氯酚胺(CC)应用前后增生期子宫内膜的厚度,放射免疫法测量血清雌二醇(E2)浓度。结果表明:CC周期第12天血E2浓度显著高于自然周期同期水平(P<0.001),而子宫内膜厚度显著较自然周期同期厚度为薄(P<0.05),相关分析示自然周期血巳浓度与子宫内膜厚度呈正相关性.而CC周期两者无相关性。提示:CC阻断E2对子宫内膜的作用,从而影响增生期子宫膜内增厚,内膜厚度与高血E2浓度不相关。
The thickness of endometrial hyperplasia before and after the application of chlorphenamine (CC) in 15 infertile women was measured by vaginal ultrasound, and the serum estradiol (E2) concentration was measured by radioimmunoassay. The results showed that the blood E2 level on the 12th day of CC cycle was significantly higher than that of the same period of the natural cycle (P <0.001), while the thickness of the endometrium was significantly thinner than that of the natural period (P <0.05). The correlation analysis showed The natural period blood concentration has a positive correlation with the endometrial thickness. There is no correlation between the CC cycles. Tip: CC block the role of E2 on the endometrium, thereby affecting the proliferative uterine membrane thickening, endometrial thickness and high blood E2 concentration is not related.