46例病理诊断的AFP阴性肝占位性病变病人的血清铁蛋白(SF)和酸性铁蛋白(SAF)放射免疫测定结果。结果表明,在这些病人中,原发性肝癌病人约占一半;SF和SAF的放免测定对AFP阴性肝占位性病变的性质具有一定的鉴别诊断价值、有助于对AFP阴性原发性肝癌(HCC)的诊断。SF和SAF放免测定诊断HCC的敏感性分別为57.1%和76.2%,特异性分別为96.0%和100%,诊断准确性分别为78.3%和89.1%。结果提示,对AFP阴性HCC的诊断价值,SAF优于SF。 Radioimmunoassay results of serum ferritin (SF) and acid ferritin (SAF) in 46 patients with pathologically diagnosed AFP-negative hepatic space-occupying lesions. The results showed that among these patients, about half were primary liver cancer patients; radioimmunoassay of SF and SAF had a certain differential diagnostic value for the nature of AFP-negative hepatic space-occupying lesions and was helpful for AFP-negative primary liver cancer. Diagnosis of (HCC). The sensitivity of SF and SAF radioimmunoassay for diagnosis of HCC was 57.1% and 76.2%, and the specificity was 96.0% and 100%, respectively. The diagnostic accuracy was 78.3% and 89.1%, respectively. The results suggest that SAF is superior to SF in the diagnostic value of AFP-negative HCC.