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目的观察中药复方益寿调脂片防治高脂血症的作用。方法采用临床和实验方法观察益寿调脂片调脂的作用。结果①益寿调脂片对高脂血症患者及实验性高脂血症大鼠能显著降低血清总胆固醇（ＴＣ）、甘油三酯（ＴＧ）、动脉粥样硬化指数（ＡＩ）、载脂蛋白Ｂ（ａｐｏＢ）、脂蛋白（ａ）［Ｌｐ（ａ）］和升高高密度脂蛋白（ＨＤＬ）、载脂蛋白Ａ（ａｐｏＡ）（Ｐ＜０．００１）；②益寿调脂片能明显对抗实验性高脂血症家兔血清总胆固醇、甘油三酯、动脉粥样硬化指数，载脂蛋白Ｂ、脂蛋白（ａ）、氧化型低密度脂蛋白（ＯＸ－ＬＤＬ）的升高和高密度脂蛋白、载脂蛋白Ａ的降低（Ｐ＜０．００１）。结论益寿调脂片具有预防和治疗高脂血症作用。
Objective To observe the effect of Yishou Tiaozhi Tablet on prevention and treatment of hyperlipidemia. Methods Clinical and experimental methods were used to observe the effect of Yishou Tiaozhi Tablet on fat regulation. Results 1 Yishou Tiaozhi Tablet can significantly reduce serum total cholesterol (TC), triglyceride (TG), atherosclerosis index (AI), apolipoprotein in hyperlipidemic patients and experimental hyperlipidemic rats. Protein B (apoB), lipoprotein (a) [Lp(a)] and elevated high-density lipoprotein (HDL), apolipoprotein A (apoA) (P<0.001); Obviously counteracts the increase of serum total cholesterol, triglyceride, atherosclerosis index, apolipoprotein B, lipoprotein (a), and oxidized low-density lipoprotein (OX-LDL) in experimental hyperlipidemia rabbits. Decrease in high-density lipoprotein and apolipoprotein A (P<0.001). Conclusion Yishou Tiaozhi Tablet can prevent and treat hyperlipidemia.