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目的:分析脑外伤患者术后继发颅内感染的相关因素。方法:对来我院接受手术治疗的450例脑外伤患者的临床资料进行回顾性分析,并对比分析未发生颅内感染(即非感染组)患者与发生感染(即感染组)患者的情况。结果:脑外伤术后继发颅内感染的概率为10.2%;细菌检出率为39.1%;其中,颅内感染的相关因素包括开放性颅脑损伤、手术前GCS评分、短期内进行两次及以上手术、手术时间超过5h、高龄、连续两侧开颅术、切口脑脊液出血渗漏,以及术后患者发生低蛋白血症等。结论:颅内感染大多发生在重型的脑外伤开颅手术后,其高危因素包括手术时间、次数,以及切口脑脊液发生渗漏等。对于带有高危因素的脑外伤患者,医护人员在手术前后应当对其各项身体指标进行严密监测,并做好预防处理工作。
Objective: To analyze the related factors of secondary intracranial infection in traumatic brain injury patients. Methods: The clinical data of 450 patients with traumatic brain injury admitted to our hospital were analyzed retrospectively. The patients without intracranial infection (ie, non-infected group) and those with infection (ie infected group) were analyzed comparatively. Results: The probability of secondary intracranial infection after traumatic brain injury was 10.2%. The detection rate of bacteria was 39.1%. Among them, the related factors of intracranial infection included open craniocerebral injury, preoperative GCS score, short-term And the above surgery, operation time more than 5h, advanced age, continuous craniotomy, leakage of cerebrospinal fluid leakage, and postoperative patients with hypoproteinemia. Conclusion: Most intracranial infections occur after craniocerebral trauma in patients with severe traumatic brain injury. The risk factors include operative time and frequency as well as leakage of incisional cerebrospinal fluid. For patients with traumatic brain injury with risk factors, medical and nursing staffs should closely monitor their various body indexes before and after the operation and do preventive work.