树突状细胞(Dendritic cell,DC)是目前发现的抗原递呈功能最强的专职抗原递呈细胞,在抗肿瘤免疫中发挥着重要的作用。随着体外扩增DC和制备DC疫苗技术的发展,DC疫苗日益成为肝癌和其它肿瘤治疗的研究热点。本文就DC的生物学特性、肝癌患者DC的特点、抗原的负载方法及其研究现状等作一综述 Dendritic cells (DCs) are currently the most fully committed antigen presenting cells for antigen presentation and play an important role in anti-tumor immunity. With the in vitro expansion of DC and the development of DC vaccine technology, DC vaccine is increasingly becoming a research hotspot in the treatment of liver cancer and other tumors. This review summarizes the biological characteristics of DC, the characteristics of DC in patients with liver cancer, the loading methods of antigen and its research status