周期性麻痹是神经科常见病,一般诊断不难,但首次发病且临床表现特殊者早期易误诊,现报告两倒并分析误诊原因。例1:女性,32岁。因四肢无力14小时,加重伴呼吸困难两小时入院。病前3周有“上感”病史。查体:T36.3,P80.R24,Bp16/10kPa。神志清,说话无力,呼吸表浅。颅神经无异常。颈肌无力,不能抬头,四肢肌张力低,肌力0～1°,腱反射弱,病理反射(一),无感觉障碍。初诊:格林-巴利综合征。因呼吸肌麻痹,于入院3小时后行气管切开术,于入院18小时后四肢肌力、肌张力和呼吸均 Cyclical paralysis is a common neurological disease, the general diagnosis is not difficult, but the first time the incidence and special clinical manifestations of early misdiagnosis, are now reported two down and analyze the causes of misdiagnosis. Example 1: Female, 32 years old. 14 hours due to weakness in limbs, increased with difficulty breathing two hours admitted to hospital. 3 weeks before the illness “sense of” history. Physical examination: T36.3, P80.R24, Bp16 / 10kPa. Consciousness, weakness, superficial breathing. No abnormal cranial nerve. Neck muscle weakness, can not be looked up, limb muscle tension is low, muscle strength 0 ~ 1 °, tendon reflex weak, pathological reflex (a), no sensory disturbance. New diagnosis: Guillain-Barre syndrome. Due to paralysis of respiratory muscle, tracheotomy was performed 3 hours after admission. Muscle strength, muscle tension and respiration of the limbs were all 18 hours after admission