论文部分内容阅读
目的 :探讨一种新的过继免疫治疗肝癌方法。方法 :将肝癌细胞株 (H2 2 )接种于近交系 BAL B/ c小鼠皮下 ,制成荷瘤小鼠模型 ,用 IL - 2 / AK细胞 /抗白介素 2受体α链单抗 (a IL - 2 Rα MAb)治疗 ,以发现其抗肿瘤作用。结果 :荷瘤小鼠脾淋巴细胞 NK活性无明显变化 ,L AK和 CTL
Objective: To explore a new method of adoptive immunotherapy for liver cancer. METHODS: Hepatoma cell line (H2 2) was inoculated subcutaneously into inbred BAL B/c mice to prepare a tumor-bearing mouse model with IL-2 / AK cells / anti-interleukin 2 receptor alpha chain monoclonal antibody (a). Treatment with IL-2Rα MAb) to find its anti-tumor effect. Results: There was no significant change in NK activity of spleen lymphocytes in tumor-bearing mice. L AK and CTL