目的　进一步提高对隆凸性皮肤纤维肉瘤 (DFSP)的认识 ,探讨正确和规范手术治疗的重要性。方法对119例隆凸性皮肤纤维肉瘤 ,进行临床和病理资料的回顾性分析。结果　 119例中有 111例 (占 93.3% )在入院前被误诊为良性肿瘤而行局部切除术 ,经补充广泛切除、病理检查最终明确局部有肿瘤残留者 5 7例 ,占 5 1 4 % ,其中 4 0例 (占 70 2 % )在查体或B超检查时未能发现残留灶 ;12例 (占 10 1% )出现纤维肉瘤样改变 (DFSP -FS) ,其中 10例见于局部切除或广泛切除后复发的病例 (复发次数 1～ 13次不等 )。结论　为避免误诊 ,临床医师有必要进一步提高对DFSP的认识 ;在局部切除术后 ,一经病理检查确诊为DFSP ,必须施行补充广泛切除以避免肿瘤残留 ;为减少复发 ,宜重视首次手术的正确治疗和广泛切除手术的规范治疗。 Objective To further understand the understanding of proton Dermatofibrosarcoma (DFSP) and explore the importance of correct and standardized surgical treatment. Methods A retrospective analysis of 119 cases with protuberant cutaneous fibrosarcoma was performed. Results A total of 111 cases (93.3%) were misdiagnosed as benign tumors prior to admission, and underwent partial resection. After extensive resection, the pathological results showed that there were 57 cases with localized tumor residues (51.4% Fourteen of them (70.2%) failed to detect residual lesions at the time of examination or B-ultrasound. Fibrosarcoma-like changes (DFSP-FS) occurred in 12 cases (101%), of which 10 cases were found in partial resection or After extensive resection of the recurrence of the cases (recurrences ranging from 1 to 13 times). Conclusion In order to avoid misdiagnosis, it is necessary for clinicians to further improve their understanding of DFSP. After DF, once the DFSP has been confirmed by pathological examination, extensive resection should be performed to avoid residual tumor. To reduce the recurrence, the correct treatment of the first operation should be emphasized And extensive excision of the normative treatment.