The true stress-strain curves of Ti-6Al-2Zr-1Mo-1V alloy were achieved by a series of isothermal compression tests with height reduction of 60% under the deformation temperatures of 1073-1323 K and the strain rates of 0.01-10s 1.The critical conditions for the onset of DRX were attained when the value of d /d,where strain hardening rate d /d,reached the minimum which corresponds to an inflection of θ versus σ curve.Thus,two important potential parameters,critical strain and critical stress,were identified,and expressed as εc/εp=0.37-0.60,σc/σp=0.81-0.91.Furthermore,by the regression analysis for conventional hyperbolic sine equation,the main material parameters such as α,β,n,and DRX activation energy,Q,were calculated.In addition,the evolution of Q with strain rate and temperature was revealed as a 3D response surface. The true stress-strain curves of Ti-6Al-2Zr-1Mo-1V alloy were achieved by a series of isothermal compression tests with height reduction of 60% under the deformation temperatures of 1073-1323 K and the strain rates of 0.01-10 s 1 . The critical conditions for the onset of DRX were attained when the value of d / d, where the minimum hardening of d / d, reached the minimum which corresponds to an inflection of θ versus σ curve.Thus, two important potential parameters, critical strain and critical stress, were identified and expressed as εc / εp = 0.37-0.60, σc / σp = 0.81-0.91. According to the regression analysis for conventional hyperbolic sine equation, the main material parameters such as α, β, and DRX activation energy, Q, were calculated. In addition, the evolution of Q with strain rate and temperature was revealed as a 3D response surface.