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目的:比较利培酮与利他林治疗儿童多动症的临床疗效及副反应。方法:将60例儿童多动症患者随机分成两组分别给予利培酮及利他林治疗,在治疗前及治疗12周未用多动指数量表(Conners)、治疗副反应量表(TESS)进行评比比较。结果:利培酮和利他林治疗的患者在治疗12周末多动指数总分和行为总分均较治疗前显著降低;但在治疗12周末利培酮组的行为总分较利他林组明显降低;两组在副反应发生率和严重程度均无显著性差异。结果:利培酮治疗儿童多动症症状和注意缺陷的效果与利他林相当,但对行为障碍的总体改善程度要优于利他林。
Objective: To compare the clinical efficacy and side effects of risperidone and ritalin in children with ADHD. Methods: Sixty children with ADHD were randomly divided into two groups and were given risperidone and risperidone respectively. Before the treatment and 12 weeks after treatment, they did not use the Conners and TESS Compare Results: Risperidone and Ritalin treatment patients in the end of 12 weeks of treatment, the total score and the total score of behavioral scores were significantly lower than before treatment; but in the treatment of risperidone group at 12 weeks the total score of activity was significantly lower than that of ritalin group There was no significant difference between the two groups in the incidence and severity of side effects. RESULTS: Risperidone was as effective as Ritalin in treating ADHD symptoms and attentional deficits, but overall improvement in behavioral disorders was superior to Ritalin.