患者男，43岁。因不规则发热伴皮肤逐渐变黑5个月，纳差、恶心、呕吐1个月，加重10天于1991年9月20日入院。患者于1991年4月开始出现间断性发热，体温37．5－39℃，伴有全身皮肤逐渐变黑。经取中药及解热止痛药体温有所下降。遂到省级医院就诊，诊断为“原发性肾上腺皮质功能低 Male patient, 43 years old. Due to irregular fever with the skin gradually darken for 5 months, anorexia, nausea, vomiting for 1 month, aggravating 10 days in September 20, 1991 admission. Patients began intermittent fever in April 1991, body temperature 37.5-39 ℃, accompanied by systemic darkening of the skin. After taking Chinese medicine and antipyretic analgesics body temperature decreased. Then to the provincial hospital for treatment, diagnosed as "primary adrenal insufficiency