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研究证实~([1]),摄取适量硒可有效预防肿瘤疾病发生及进展,且能显著降低癌症患者病死率,在一定程度上改善肿瘤细胞的生长抑制及血管内皮生长因子(VEGF)表达水平[2]。血管生成在肿瘤发病、侵袭及转移过程中具有重要作用,VEGF在膀胱癌、消化道肿瘤及造血系统肿瘤中均呈高表达,证实了VEGF在肿瘤中的作用[3]。本研究探讨硒对肝癌细胞的生长抑制及VEGF表达水平的影响。1资料与方法
Study confirmed ~ ([1]), adequate intake of selenium can effectively prevent tumor progression and progression, and can significantly reduce the mortality of cancer patients, to some extent, improve the growth inhibition of tumor cells and vascular endothelial growth factor (VEGF) expression levels [2]. Angiogenesis plays an important role in the pathogenesis, invasion and metastasis of tumor. VEGF is highly expressed in bladder cancer, gastrointestinal cancer and hematopoietic tumor, which confirms the role of VEGF in tumor [3]. This study was to investigate the effects of selenium on the growth inhibition of hepatoma cells and the expression of VEGF. 1 data and methods