髓芯减压和骨髓基质细胞移植对家兔股骨头缺血性坏死的治疗作用

来源 :中国临床解剖学杂志 | 被引量 : 0次 | 上传用户:sunjuanhuahard
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目的:探讨髓芯减压和体外培养的同种异体骨髓基质细胞移植,对兔股骨头缺血性坏死的治疗作用和修复机制。方法:采用新西兰大白兔液氮冷冻法造模,随机分为髓芯减压(A)组和同种异体细胞移植(B)组。术后标本做X-线和组织学观察。结果:(1)X-线观察2周时A、B组股骨头钻孔区边缘密度增加;8周时A组钻孔区呈低密度,边缘形成硬化线,B组钻孔区出现骨小梁结构。(2)组织学观察2周时A组钻孔区边缘出现较多的成骨细胞,并有骨组织形成;8周时钻孔区形成骨髓组织;2周时B组钻孔区有大量的成骨细胞,边缘有较多的骨组织形成:4周时
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