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目的 检测正常儿童彩色图形视觉诱发电位 (CP VEP)的特征 ,以探讨其正常参考值及CP VEP方法学特点。方法 用计算机软件技术 ,PR 65 0分光测色计严格控制亮度和颜色因素 ,采用保留颜色对比、降低亮度对比的方法 ,设置了黑 白、灰 白、红 白、绿 白、红 灰、绿 灰、红 绿七种棋盘格视觉刺激条件 ,对 45例 (90眼 )正常儿童进行CP VEP检测。结果 (1)正常儿童七种刺激条件下均能记录到稳定的NPN复合波 ,左、右眼P1波潜伏期和振幅比较无显著性差异 (P >0 0 5 )。 (2 )亮度对比联合色觉对比的三种刺激 ,按红 白格、灰 白格、绿 白格顺序 :P1波潜伏期依次为 110 4± 3 9ms、 111 8± 4 8ms、 111 7± 4 2ms ,差异无显著性 ,P1波振幅的比较无统计学差异。(3 )单纯色觉对比的三种刺激 ,按红 灰格、红 绿格、绿 灰格顺序P1波潜伏期依次为 116 1± 5 4ms、119 0± 9 2ms、 13 2 5± 14 9ms ,绿 灰格比红 绿和红 灰格分别延长 12 6ms和 16 4ms ,差异有显著性 ,红 绿格与红 灰格比较无统计学差异 ,P1波振幅的比较无统计学差异。结论 我们的研究将为临床提供正常参考值及方法学参考
Objective To detect the characteristics of normal children’s color vision visual evoked potential (CP VEP) to explore its normal reference value and CP VEP methodological features. Methods Using the computer software technology, the PR 65 0 spectrophotometer strictly controlled the brightness and color factors. The methods of preserving the color contrast and reducing the contrast of brightness were set up. The methods of black and white, gray, red and white, green and white, red and gray, green and gray, red Green seven kinds of checkerboard visual stimulation conditions, 45 cases (90 eyes) of normal children CPVEP detection. Results (1) The stable NPN complex was recorded in all seven stimuli of normal children. There was no significant difference in the latency and amplitude of P1 between left and right eyes (P> 0.05). (2) The contrast of brightness with the combination of three color vision contrast stimulation, according to the order of red and white grid, gray grid and green grid. The latency of P1 wave was 110 4 ± 39ms, 111 8 ± 48ms and 111 7 ± 42ms, respectively No significant, P1 wave amplitude comparison no significant difference. (3) Compared with the three stimuli of simple color vision, the latency of P1 wave in order of red-gray grid, red-green grid and green-gray grid were 116 ± 5 ms, 119 ± 9 2 ms, 13 2 ± 14 9 ms, The ratio of red, green and red and gray was extended 12 6ms and 16 4ms respectively, the difference was significant. There was no significant difference between red and green cells and red and gray cells, and there was no significant difference in P1 wave amplitude. Conclusions Our research will provide normal reference value and methodological reference for clinic