论文部分内容阅读
目的探讨口服硫酸沙丁胺醇与丙卡特罗改善支气管哮喘患儿肺功能临床效果差异。方法选择我院2010年4月至2012年4月支气管哮喘急性发作患儿共80例,上述患儿随机分为观察组和对照组。两组患儿入院治疗前均测定肺功能,而后给予异丙托溴铵1 ml联合沙丁胺醇雾化吸入。观察组患儿在上述用药基础上给予硫酸沙丁胺醇缓释胶囊,对照组患儿同时给予丙卡特罗片。测定两组治疗前和治疗14 d后肺功能情况。结果观察治疗14 d后FEV1%和PEF%分别与本组治疗前比较,差异有统计学意义(P<0.05);对照组治疗14 d后FEV1%和PEF%分别与本组治疗前比较,差异有统计学意义(P<0.05);观察组治疗后差异有统计学意义(P<0.05)和对照组治疗后比较,差异无统计学意义(P>0.05)。结论口服硫酸沙丁胺醇与丙卡特罗改善支气管哮喘患儿肺功能方面临床效果相同,但口服沙丁胺醇起效慢口服不能立即缓解急性发作患儿临床症状。
Objective To investigate the clinical effects of salbutamol sulphate and procaterol in improving pulmonary function in children with bronchial asthma. Methods A total of 80 children with acute bronchial asthma were selected from April 2010 to April 2012 in our hospital. The children were randomly divided into observation group and control group. Both groups of children were admitted to hospital before treatment were measured pulmonary function, and then given ipratropium bromide 1 ml combined salbutamol inhalation. Patients in the observation group were given salbutamol sulfate sustained-release capsules on the basis of the above-mentioned medication, while children in the control group were given procaterol tablets at the same time. The lung function of the two groups before treatment and after 14 days of treatment were measured. Results The FEV1% and PEF% of the FEV1% and PEF% of the control group after treatment for 14 days were significantly different from those before the treatment (P <0.05). The FEV1% and PEF% of the control group after 14 days of treatment were respectively compared with those before treatment in this group (P <0.05). The difference in the observation group after treatment was statistically significant (P <0.05) and in the control group after treatment, the difference was not statistically significant (P> 0.05). Conclusions Oral salbutamol sulphate and procaterol have the same clinical effect in improving lung function in children with bronchial asthma. However, the oral administration of oral albuterol can not immediately relieve the clinical symptoms of children with acute attack.