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目的了解本地区结核(TB)患者中乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和人类免疫缺陷病毒(HIV)感染状况及特征,为本地区TB/HBV/HCV/HIV的防治、控制方案的制定提供科学依据。方法对2007年10月-2012年12月本院收治的2 947例TB患者进行血清学检测,收集患者临床资料并行流行病学调查,分析其感染模式。结果 2947例TB患者中检出感染者573人,其中HBV、HCV和HIV感染者535、69和3人;合并感染17人,其中HBV合并抗HCV感染15人,HBV合并HIV感染2人,其中HBV&HIV&HCV感染1人。不同年龄TB患者感染率差异有统计学意义(χ2=181.08,P<0.01),不同性别TB患者感染率差异有统计学意义(χ2=28.72、7.29,P<0.01;χ2=3.93,P<0.05),不同职业TB患者感染率差异有统计学意义(χ2=217.53,P<0.01)。结论本地区TB患者HBV感染率较一般人群高,并有着不可忽视的HCV和HIV病毒感染率,且有HIV流行的趋势,属HBV、HCV和HIV感染高危人群,应引起高度重视。
Objective To investigate the status and characteristics of hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infection in tuberculosis (TB) patients in the region and to provide evidence for the prevention and control of TB / HBV / HCV / HIV in this region , The establishment of control programs to provide a scientific basis. Methods A total of 2 947 TB patients admitted to our hospital from October 2007 to December 2012 were enrolled in this study. The clinical data of the patients were collected for epidemiological investigation and their infection patterns were analyzed. Results A total of 573 people were detected in 2947 TB patients, among which 535, 69 and 3 were infected with HBV, HCV and HIV, 17 were co-infected with HBV infection and 15 were HCV infection and 2 were infected with HBV with HIV infection 1 person infected with HBV & HIV & HCV. The infection rates of TB patients of different ages were statistically significant (χ2 = 181.08, P <0.01). The infection rates of TB patients with different gender were statistically significant (χ2 = 28.72, 7.29, P <0.01; ), TB infection rates in different occupations were significantly different (χ2 = 217.53, P <0.01). Conclusion The prevalence of HBV infection in TB patients in this area is higher than that in the general population, and there is an undeniable infection rate of HCV and HIV, and there is a trend of HIV prevalence among those with high risk of HBV, HCV and HIV infection.