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肝纤维化是指肝脏慢性炎症或损伤导致肝脏及内纤维结缔组织异常增生,是所有慢性肝病共有的病理改变。目前认为肝星状细胞(HSC)的活化与增生是肝纤维化进展的中心环节[1],有众多的细胞因子参与其中,尤以转化生长因子β(TGF-β)最为关键,为此我们拟观察降纤I号对体外培养肝星状细
Liver fibrosis refers to chronic liver inflammation or damage that leads to abnormal proliferation of connective tissue in the liver and in the fibroids. It is a common pathological change in all chronic liver diseases. Currently, the activation and hyperplasia of hepatic stellate cells (HSCs) is considered to be a central link in the progression of hepatic fibrosis [1]. Numerous cytokines are involved, and in particular, transforming growth factor β (TGF-β) is the most critical. To observe the effect of defibrillation I on cultured hepatic stellate in vitro