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相对于其他腹腔恶性肿瘤,胰腺癌的发病率与死亡率近乎相同~[1]。而且即便在医学科学技术(包括靶向精准治疗)和外科技术迅速发展的今天,胰腺癌的治愈率也与20年前没有太大的变化~[2]。其重要的原因除了胰腺癌常见的易发早期转移、嗜神经性的神经转移、对放射治疗和目前的化疗药物敏感性差等,恐怕还有我们尚未认识的其他胰腺癌的生物学特性,使得胰腺癌的预后难以改善。外科性的胰腺癌根治性切除是目前公认的唯一可能治愈
Compared with other malignant tumors of the abdominal cavity, the incidence and mortality of pancreatic cancer are almost the same ~ [1]. And even in the rapid development of medical science and technology (including targeted precision therapy) and surgical techniques today, the cure rate of pancreatic cancer has not changed much compared with 20 years ago [2]. The important reason is that in addition to the common early-stage metastasis of pancreatic cancer, neuropathic nerve metastasis, poor sensitivity to radiotherapy and current chemotherapy drugs, there are other biological characteristics of pancreatic cancer that we have not yet known, so that the pancreas The prognosis of cancer is difficult to improve. Radical resection of surgical resection of pancreatic cancer is now recognized as the only possible cure