论文部分内容阅读
目的:探讨高血压脑出血后血浆脂联素(APN)浓度变化及其与C-反应蛋白水平的相关性。方法:高血压脑出血病例82例列入研究组,健康者80例列入对照组,所有受试者均于发病6小时内抽血检测APN和C-反应蛋白(CRP)。结果:研究组患者血清APN水平明显低于对照组,CRP水平明显高于对照组,差异有统计学意义(P<0.05)。随着高血压等级的升高,研究组患者APN值逐渐下降,CRP水平逐渐上升,但APN与CRP值的变化无显著差异(P>0.05)。结论:高血压脑出血后患者血浆脂联素浓度变化与CRP具有负相关性。
Objective: To investigate the changes of plasma adiponectin (APN) concentration and its correlation with C-reactive protein after hypertensive intracerebral hemorrhage. Methods: 82 cases of hypertensive intracerebral hemorrhage were enrolled in the study group and 80 healthy persons were enrolled in the control group. All subjects were tested for APN and C-reactive protein (CRP) within 6 hours after onset. Results: Serum APN levels in the study group were significantly lower than those in the control group, CRP levels were significantly higher than the control group, the difference was statistically significant (P <0.05). As the level of hypertension increased, the study group patients APN value gradually decreased, CRP level gradually increased, but APN and CRP values did not change significantly (P> 0.05). Conclusion: Plasma concentrations of adiponectin in patients with hypertensive intracerebral hemorrhage have a negative correlation with CRP.