三丁基锡(tributyltin,TBT)是一种重要的有机锡化合物,因其特有的理化性质可用作木材防腐剂,船体涂料的防污剂,纺织业、工业水系统、木浆和造纸系统以及啤酒厂的抑菌剂。大量实验研究表明TBT会对人体及动物造成危害,主要包括神经毒性、免疫毒性、肝毒性和生殖毒性等。本文将对TBT所致的毒性危害及机制进行综述。 Tributyltin (TBT) is an important organotin compound that can be used as a wood preservative, an antifouling agent for hull coatings, textile, industrial water systems, wood pulp and paper making systems, and beer for its unique physicochemical properties Factory antibacterial agent. A large number of experimental studies have shown that TBT will cause harm to humans and animals, including neurotoxicity, immunotoxicity, hepatotoxicity and reproductive toxicity. This article will review the toxic hazards and mechanisms caused by TBT.