目前已知方法制得的肝素通常是钠盐形式,活力大约80-100~(I.u)/mg·这样的粗品颜色有很大的幅度,从棕色到黄色。为了清除这种颜色曾作了许多尝试,目的在于获得一种本质上是纯净白色的产品,它的水溶液是无色的。用于漂白精制肝素的氧化剂很多,但它们不仅与有色杂质作用还和肝素发生作用,因此氧化剂的使用应严格控制。加大专刊624,095谈及了用高锰酸盐作漂白剂。次外,还提议用溴酸盐、过硼酸盐、过硫酸盐、次氯酸盐、氯酸盐、重 The currently known method of producing heparin is usually in the form of a sodium salt with a viability of about 80-100 (I.u) / mg. Such a crude product has a large range of colors, from brown to yellow. Many attempts have been made to clear this color in order to obtain an essentially pure white product whose aqueous solution is colorless. There are many oxidants used to bleach refined heparin, but they work not only with colored impurities but also with heparin, so the use of oxidants should be tightly controlled. An additional bulletin 624,095 addresses the use of permanganate as a bleaching agent. In addition, it is also proposed to use bromate, perborate, persulfate, hypochlorite, chlorate, heavy