目的　探讨儿童过敏性紫癜的抗氧化能力及与发病机制的关系。方法　对 33例儿童过敏性紫癜患儿和 2 0例健康儿童血清丙二醛、超氧化物歧化酶进行了测定、对比和t检验。结果　过敏性紫癜组丙二醛显著高于对照组 ,超氧化物歧化酶低于对照组。结论　过敏性紫癜时体内脂质过氧化水平高 ,且体内清除活性氧的能力下降。活性氧是发病的一个重要炎性介质 Objective To investigate the antioxidant capacity of children with Henoch-Schonlein purpura and its relationship with pathogenesis. Methods Serum malondialdehyde (MDA) and superoxide dismutase (SOD) in 33 children with Henoch-Schonlein purpura and 20 healthy children were measured, compared and t-test. Results The degree of malondialdehyde in allergic purpura was significantly higher than that in the control group and the superoxide dismutase was lower than that in the control group. Conclusions In patients with Henoch-Schonlein purpura, the level of lipid peroxidation in the body is high, and the ability of the body to remove reactive oxygen species is reduced. Active oxygen is an important inflammatory mediator