呼吸衰竭时由于缺氧和CO_2潴留,导致呼吸系统、循环系统和中枢神经系统的功能和全身代谢的变化,产生严重而复杂的血液酸碱平衡紊乱。同时,作为细胞外液重要组成成分的脑脊液酸碱状况在呼吸衰竭时也相应发生一系列改变。文献关于这方面的报道很多,国内近年来也开展了对慢性呼吸衰竭脑脊液酸碱平衡改变的研究,但缺乏小儿急性呼吸衰竭的资料。我们于 Respiratory failure due to hypoxia and CO2 retention, leading to the respiratory system, circulatory and central nervous system function and systemic metabolism, resulting in severe and complex blood acid-base balance disorders. At the same time, as an important component of extracellular fluid of cerebrospinal fluid acid-base condition in respiratory failure also a series of changes. Literature on this many reports, the domestic also carried out in recent years, chronic respiratory failure of cerebrospinal fluid acid-base balance changes in the study, but the lack of pediatric acute respiratory failure data. We are here