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目的探讨C-反应蛋白(CRP)、血清降钙素原(PCT)及白细胞(WBC)计数联合检测在感染性疾病诊断中的应用价值。方法 140例感染性疾病患者,将其分为细菌感染组80例、非细菌感染组60例,另选同期健康体检者60例作为对照组,分别检测、比较各组血清中CRP、WBC和PCT水平。结果细菌感染组患者血清平均CRP、WBC和PCT水平高于非细菌感染组和对照组,差异均有统计学意义(P<0.05);细菌感染组患者在感染得到控制后,其血清PCT和CRP水平迅速回落至正常水平。结论血清CRP、PCT和WBC联合检测可用于感染性疾病的诊断和鉴别诊断,动态监测血清PCT和CRP水平变化,可及时了解患者的病情变化,有助于抗生素药物的合理应用。
Objective To investigate the value of combined detection of C-reactive protein (CRP), serum procalcitonin (PCT) and white blood cell (WBC) count in the diagnosis of infectious diseases. Methods One hundred and fourteen patients with infectious diseases were divided into bacterial infection group (n = 80), non-bacterial infection group (n = 60), and the other 60 healthy subjects during the same period as control group. The serum levels of CRP, WBC and PCT Level. Results Serum CRP, WBC and PCT levels in patients with bacterial infection were significantly higher than those in non-bacterial patients and controls (P <0.05). After the infection was controlled, the serum PCT and CRP The level quickly dropped back to normal levels. Conclusions Combined detection of serum CRP, PCT and WBC can be used for the diagnosis and differential diagnosis of infectious diseases. Dynamic changes of serum PCT and CRP level can be monitored and the changes of patients’ condition can be timely understood, which is helpful for rational use of antibiotics.