论文部分内容阅读
目的:应用三维超声评价系统性红斑狼疮(SLE)患者不同程度肺动脉高压(PAH)时右心房功能的改变。方法:依据临床SLE的诊断标准将诊断明确的102例患者分为3组:A组为无PAH(肺动脉收缩压≤30mmHg,1mmHg=0.133kPa,37例),B组为轻度PAH(30mmHg<肺动脉收缩压<50mmHg,34例),C组为中重度PAH(50mmHg≤肺动脉收缩压,31例)。另筛选出相同条件下30例检查正常者为对照组。对4组患者行常规二维及三维超声心动图检查,记录并分析右心房相关参数。结果:A组指标与对照组相比差异无统计学意义(P>0.05)。B、C组主动排空容积指数(SVIact)较对照组增高,并且SVI随着肺动脉收缩压的增高而呈增高趋势。B、C组总排空分数指数(EFI)及被动排空分数指数(EFIpas)均低于对照组,并且随肺动脉收缩压的增高呈减低趋势(均P<0.05)。B、C组主动排空分数指数(EFIact)高于对照组(均P<0.05)。结论:随着SLE患者肺动脉压不同程度的增高,三维超声可以客观评价其右心房功能的变化。
Objective: To evaluate the changes of right atrial function in patients with systemic lupus erythematosus (SLE) with different degrees of pulmonary hypertension (PAH) by three-dimensional echocardiography. Methods: According to the diagnostic criteria of clinical SLE, 102 patients with definite diagnosis were divided into 3 groups: group A without PAH (pulmonary systolic pressure ≤30mmHg, 1mmHg = 0.133kPa, 37 cases), group B with mild PAH (30mmHg < Pulmonary artery systolic pressure <50mmHg, 34 cases), C group was moderate and severe PAH (50mmHg≤ pulmonary systolic pressure, 31 cases). The other 30 cases under normal conditions were selected as the control group. Four groups of patients underwent routine two-dimensional and three-dimensional echocardiography, recording and analysis of right atrial related parameters. Results: There was no significant difference between group A and control (P> 0.05). In group B and group C, the volume index of active emptying (SVIact) increased compared with the control group, and the SVI increased with the increase of pulmonary artery systolic pressure. The total score of EFI and EFIpasses of group B and group C were lower than that of control group, and decreased with the increase of pulmonary systolic pressure (all P <0.05). The EFIact scores of group B and group C were higher than that of control group (all P <0.05). CONCLUSIONS: With the increase of pulmonary arterial pressure in patients with SLE, three-dimensional ultrasound can objectively evaluate the changes of right atrial function.