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阻塞型睡眠呼吸暂停综合征是一种常见的睡眠障碍性疾病。阻塞型睡眠呼吸暂停综合征常与肥胖症共存,且已证实阻塞型睡眠呼吸暂停综合征与心血管疾病有联系。因此,阻塞型睡眠呼吸暂停综合征可能对肥胖相关性心血管疾病发生发展起作用。这篇综述主要阐述阻塞型睡眠呼吸暂停综合征、肥胖症、心血管疾病之间的病理生理学的交互作用,以及进一步关于阻塞型睡眠呼吸暂停综合征研究的潜在暗示含义。
Obstructive sleep apnea syndrome is a common sleep disorder. Obstructive sleep apnea syndrome often coexists with obesity, and it has been shown that obstructive sleep apnea syndrome is associated with cardiovascular disease. Therefore, obstructive sleep apnea syndrome may play a role in the development of obesity-related cardiovascular diseases. This review focuses on the pathophysiological interactions between obstructive sleep apnea syndrome, obesity and cardiovascular disease, and potential implications for further research into obstructive sleep apnea syndrome.