经肛内窥镜微创手术是更快和更安全的替代传统手术治疗腺瘤和低危险(T1期)直肠癌的方法,但其有较高的复发率。为探讨经肛内窥镜微创手术后局部复发患者的治疗并评估其远期效果,Stipa等人进行了一项病例资料的回顾性研究。该研究纳入了1990～2011年期间罗马大型三级保健医院298例经肛内窥镜微创手术行肿瘤局部切除术(全层切除)的直肠腺癌患者,分析患者的特征、手术资料、病理诊断和肿瘤复发情况,应用Kaplan-Meyer法分析生存率,log-rank检验比较组间差异。结果显示:肿瘤分期为pT1期86例(59.7%),pT2期38例(26.4%),pT3期20例(13.9%);中位随访时间85个月(3～234 Trans-anal endoscopic minimally invasive surgery is a faster and safer alternative to traditional surgeries for adenomas and low-risk (T1) rectal cancers, but it has a high recurrence rate. To investigate the treatment of patients with local recurrence after minimally invasive endoscopic surgery and to assess their long-term outcomes, a retrospective study was conducted by Stipa et al. The study included 298 patients with rectal adenocarcinoma who underwent endoscopic tumor resection (full-thickness resection) with minimally invasive endoscopic surgery between 1990 and 2011 in Rome’s large tertiary care hospitals. The characteristics, surgical data, pathology Diagnosis and tumor recurrence, Kaplan-Meyer analysis of survival rate, log-rank test to compare the differences between groups. The results showed that the tumor stage was 86 cases (59.7%) in pT1 stage, 38 cases (26.4%) in pT2 stage and 20 cases (13.9%) in pT3 stage. The median follow-up time was 85 months