论文部分内容阅读
目的:通过不同时间间隔鼓室内注射地塞米松治疗突发性聋的临床疗效对比,探讨鼓室内注射的适当时间间隔。方法:临床确诊160例突聋患者,除给予常规扩张血管、溶栓、高压氧治疗,同时给予鼓室腔内灌注地塞米松,按不同时间间隔分为3组。每日注射组:每日给予患耳鼓室腔内注射;隔日注射组:隔日注射;1周2次组:1周注射2次。另有全身使用激素组28例及未用激素组18例。共计206例患者。结果:每日注射组和隔日注射组疗效差异无统计学意义,与1周2次组、全身使用激素组及未用激素组比较,差异有统计学意义。结论:鼓室腔注射地塞米松临床应用广泛,操作简单,疗效明显,每日及隔日一次注射患者依从性好,疗效较1周2次明显,避免了全身使用糖皮质激素的不良反应,患者无明显痛苦,可推广应用。
OBJECTIVE: To compare the clinical efficacy of intratympanic injection of dexamethasone for sudden deafness at different intervals and to explore the proper time interval for intratympanic injection. Methods: 160 patients with sudden deafness were diagnosed clinically. Except for routine dilation of blood vessels, thrombolytic therapy and hyperbaric oxygen therapy, dexamethasone was infused into the tympanic cavity at different time intervals and divided into 3 groups. The daily injection group: daily given to the tympanic cavity intracavitary injection; every other day injection group: every other day injection; 1 week 2 times group: 1 week injection 2 times. Another systemic use of hormones in 28 cases and no hormones in 18 cases. A total of 206 patients. Results: There was no significant difference in the curative effect between daily injection group and every other day injection group. The difference was statistically significant compared with the two groups at one week, the systemic hormone group and the non-hormone group. Conclusion: The application of dexamethasone in tympanic cavity is extensive, simple and easy to operate. The curative effect is obvious. The daily compliance and daily injection are good. The curative effect is better than that of twice a week, which avoids the systemic adverse reactions of glucocorticoids. Obvious pain, can promote the application.