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高渗性非酮症性糖尿病昏迷(NHDC)又名高渗性糖尿病昏迷(HDC),1957年Sament及Degraeff首先报道本症,国内1973年首都医院首次报道3例。本症2/3患者既往无显性糖尿病病史,是糖尿病的严重并发症,病死率高达40%～70%,临床以高渗高糖及细胞内脱水为重要特征,以意识障碍及循环衰竭为主要表现,主要诱因是感染及脱水。近年来流行性出血热(EHF)并发NHDC时有发生,现将本症综述如下。
Hyperosmolar non-ketotic diabetic coma (NHDC), also known as hypertonic diabetic coma (HDC), 1957 Sament and Degraeff first reported the disease, the first report in 1973, Capital Hospital in China 3 cases. 2/3 of patients with past disease history of non-obvious diabetes mellitus, is a serious complication of diabetes, mortality rate as high as 40% to 70%, clinical hypertensive hyperglycemia and intracellular dehydration as an important feature of consciousness disorders and circulatory failure as The main performance, the main cause is infection and dehydration. In recent years, epidemic hemorrhagic fever (EHF) concurrent NHDC have occurred, now the disease are summarized below.