论文部分内容阅读
目的:观察重组人表皮生长因子(金因肽,rhEGF)治疗儿童复发性口腔溃疡(RAU)的疗效。方法:109例复发性口腔溃疡患儿随机分为实验组57例,用金因肽喷于溃疡表面,3次/d;对照组52例用西瓜霜喷于溃疡表面,3次/d;比较两组溃疡愈合情况。结果:疼痛消失的时间实验组(3.92±1.53)天,对照组(5.09±2.07)天,两组比较差异有统计学意义(P<0.01);溃疡愈合时间实验组(4.97±2.21)天,对照组(6.22±2.90)天,两组比较差异有统计学意义(P<0.01)。结论:金因肽治疗儿童复发性口腔溃疡可缩短疼痛和治愈时间,值得临床推广。
Objective: To observe the effect of recombinant human epidermal growth factor (rhEGF) on children with recurrent oral ulcer (RAU). Methods: A total of 109 children with recurrent oral ulcer were randomly divided into experimental group (n = 57), treated with gold peptide injection on the surface of ulcer for 3 times a day, and control group (n = 52) treated with watermelon cream on the surface of ulcer for 3 times per day. Two groups of ulcer healing. Results: The pain disappeared in the experimental group (3.92 ± 1.53) days, the control group (5.09 ± 2.07) days, the difference between the two groups was statistically significant (P <0.01); ulcer healing time in the experimental group (4.97 ± 2.21) days, The control group (6.22 ± 2.90) days, the difference between the two groups was statistically significant (P <0.01). Conclusion: Treatment of recurrent aphthous ulcer in children with gold peptide can shorten the pain and cure time, which is worthy of clinical promotion.