论文部分内容阅读
[目的]了解本地区人群中乙肝病毒(HBV)感染情况,为制定控制措施,调整防控策略提供依据。[方法]采取非比例分层随机抽样法抽取我市城乡1～82岁普通人群1944份血样,用酶联免疫吸附试验(ELISA)检测乙肝病毒血清标志物表面抗原(HBsAg)、表面抗体(抗-HBs)和核心抗体(抗-HBc),分别统计HBsAg携带率与HBV感染率。[结果]1944例调查对象HBsAg携带率7.25%,HBV感染率58.64%;HBsAg携带率和HBV感染率16岁以上年龄组人群高于16岁以下的低年龄组(χ2=27.35,P﹤0.05;χ2=189.54,P﹤0.05),HBsAg携带率无性别差异,HBV感染率女性高于男性(χ2=13.29,P﹤0.05),城乡2项指标均无差异(χ2=0.00,P﹥0.05),未接种乙肝疫苗人群高于已接种乙肝疫苗人群(χ2=37.94,P﹤0.05;χ2=246.07,P﹤0.005)。[结论]与2006年全国人群乙肝血清流行病学调查结果相比,泸州市一般人群HBsAg携带率与HBV感染率与全国水平相当,但性别分布有差异。
[Objective] To understand the status of hepatitis B virus (HBV) infection in population in this area and provide the basis for making control measures and adjusting prevention and control strategies. [Method] A total of 1944 blood samples from general population from 1 to 82 years old in urban and rural areas of our city were collected by non-proportional stratified random sampling method. Serum markers of surface antigen (HBsAg), surface antibody (anti-HBsAg) were detected by enzyme-linked immunosorbent assay -HBs) and core antibody (anti-HBc), respectively, statistics HBsAg carrier rate and HBV infection rate. [Results] 1944 cases of HBsAg carrier rate of 7.25%, HBV infection rate of 58.64%; HBsAg carrier rate and HBV infection rate of over 16 years old group was higher than the age group under 16 years old (χ2 = 27.35, P <0.05; (χ2 = 189.54, P <0.05). There was no gender difference in the carrier rate of HBsAg. The HBV infection rate in female was higher than that in male (χ2 = 13.29, P <0.05) The population without hepatitis B vaccine was higher than those with hepatitis B vaccine (χ2 = 37.94, P <0.05; χ2 = 246.07, P <0.005). [Conclusion] Compared with the results of serological survey of hepatitis B in the whole nation in 2006, the incidence of HBsAg and HBV infection in the general population in Luzhou are similar to that of the whole country, but the gender distribution is different.