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目的:分析胎膜早破孕妇宫颈分泌物培养结果,了解感染病原体的分类及对妊娠结局的影响。方法:选取诊断为胎膜早破的孕妇136例为观察对象(观察组),同期正常产检无胎膜早破孕妇136例为对照组,取宫颈分泌物进行培养检查。结果:观察组共检出病原体122例(89.71%),前三位分别为混合感染39例(28.68%)、革兰氏阳性菌(G+)35例(25.74%)、支原体感染17例(12.50%);对照组检出病原体33例(24.26%)。胎膜早破孕妇G+菌、G-菌、真菌、支原体、衣原体、混合感染检出率明显高于无胎膜早破孕妇,两组孕妇各类病原体检出率差异有统计学意义(P<0.05);早产、剖宫产、低出生体重儿、胎儿窘迫、新生儿窒息发生率胎膜早破孕妇明显高于未发生胎膜早破孕妇,两组差异有统计学意义(P<0.05)。结论:孕妇宫颈病原体感染与胎膜早破发生密切相关,感染可导致妊娠不良结局发生几率增加。
Objective: To analyze the results of cervical secretions culture in premature rupture of membranes and to understand the classification of infectious pathogens and its effect on pregnancy outcome. Methods: One hundred and sixty-six pregnant women diagnosed as premature rupture of membranes were selected as observational group. In the same period, 136 pregnant women without premature rupture of membranes were selected as the control group. Cervical secretions were taken for culture examination. Results: A total of 122 pathogens (89.71%) were observed in the observation group. The first three cases were mixed infection in 39 cases (28.68%), Gram-positive bacteria in 35 cases (25.74%), mycoplasma infection in 17 cases %). The control group detected 33 pathogens (24.26%). The detection rate of G + bacteria, G- bacteria, fungi, mycoplasma, chlamydia and mixed infection in pregnant women with premature rupture of membranes was significantly higher than that of pregnant women without premature rupture of membranes. There was significant difference in the detection rate of various pathogens in both groups (P < 0.05) .The premature rupture of membranes, cesarean section, low birth weight infants, fetal distress and neonatal asphyxia premature rupture of membranes were significantly higher in pregnant women than in those without premature rupture of membranes, the difference was statistically significant (P <0.05) . Conclusion: The infection of cervical pathogen in pregnant women is closely related to premature rupture of membranes, and the infection may lead to the increase of adverse pregnancy outcome.