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本文对近年来有关妇科癌症复发治疗研究的进展加以综述,着重介绍了新的手术加放疗、盆腔脏器去除术、术中放疗及新辅助化疗等治疗妇癌复发的方法。对放疗后盆壁复发行手术加放疗、中央性复发行盆腔脏器去除术似为有效的根治方法。对在腹主动脉旁或盆壁复发的患者在减瘤术后行术中放疗可提高放射野内有效控制率和5年存活率。以异环磷酰胺和铂类化合物为主的化疗为一些被认为不治之症的妇癌复发患者提供了新的治疗希望。
This review summarizes recent progress in the research of gynecologic cancer recurrence and focuses on the introduction of new methods of surgery plus radiotherapy, pelvic organ removal, intraoperative radiotherapy and neoadjuvant chemotherapy for the treatment of recurrence of cancer. Pelvic recurrence after radiotherapy combined surgery and radiotherapy, recurrent central pelvic organ resection seems to be effective radical method. Intraoperative radiotherapy in patients with recurrence of the abdominal aorta or pelvic wall after tumor reduction can improve the effective control of radiation field and 5-year survival rate. Chemotherapy with ifosfamide and platinum-based compounds offers new therapeutic hope for some patients with recurrent cancer who are considered incurable.