作者用混合的松节油和花生油注入大白鼠头顶骨骨膜下,3～8天引起肉芽肿。在光镜下肉芽肿局部骨破坏重吸收,破骨细胞和吸收的骨表面相接触,有许多纤维母细胞与破骨细胞密切接触。纤维母细胞的长突伸到吸收的骨表面,其胞突的空泡处有吞噬的骨胶原微纤维,类似这种吞噬现象有在破骨细胞内看到。 The authors injected turpentine oil and peanut oil into the suborbital periosteum of rats and caused granulomas within 3 to 8 days. Under light microscopy, the granulomas partially re-absorb bone destruction, and the osteoclasts come into contact with the absorbed bone surface. Many fibroblasts are in close contact with the osteoclasts. Long fibroblasts project to the surface of the absorbed bone, and the phagocytic vesicles of collagen microfibrils are found in the vacuoles of the cytoplasm, similar to the phagocytosis seen in osteoclasts.