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目的:探讨双源CT双能量肺灌注成像(DEPI)与肺动脉造影(CTPA)相结合对肺栓塞患者的诊断价值。方法:对50例临床怀疑肺栓塞患者进行CT双能量肺灌注成像。采用Lung PBV软件进行数据后处理,可以得到DEPI、CTPA以及两者的融合图像。通过DEPI、CTPA及两者联合检测三种方法,对肺叶、肺段及亚段水平肺栓塞诊断结果分别进行两两比较的χ2检验,分析其结果差异有无统计学意义。结果:通过χ2检验发现,在肺叶水平,DEPI、CTPA及两者联合诊断肺栓塞结果差异均无统计学意义(P>0.05);在肺段及亚段水平,三种方法比较均有统计学意义(P<0.05),尤其在亚段水平联合诊断提高了对孤立亚段肺栓塞的检出率。结论:通过将功能性的DEPI与解剖性的CTPA相结合应用既提高了诊断肺栓塞的敏感度,又保留了较高的特异度,对早期准确诊断肺栓塞有重要作用,有助于指导临床及时治疗及预后评估。
Objective: To investigate the diagnostic value of dual-source CT dual-energy perfusion imaging (DEPI) and pulmonary angiography (CTPA) in patients with pulmonary embolism. Methods: Fifty patients with clinically suspected pulmonary embolism underwent CT dual-energy lung perfusion imaging. Lung PBV software for data post-processing, you can get DEPI, CTPA and the fusion of the two images. By DEPI, CTPA and the combination of the three detection methods, lung lobes, lung segments and sub-levels of pulmonary embolism were two-to-one comparison χ2 test results, analysis of the differences were statistically significant. Results: There was no significant difference in pulmonary embolism between DEPI, CTPA and pulmonary embolism detected by χ2 test (P> 0.05). There were statistically significant differences between the three methods (P <0.05), especially in the sub-level combined diagnosis of isolated sub-pulmonary embolism increased the detection rate. Conclusion: The combination of functional DEPI and anatomical CTPA not only increases the sensitivity of diagnosis of pulmonary embolism, but also retains high specificity, which has an important role in the early diagnosis of pulmonary embolism and helps to guide the clinical Timely treatment and prognosis assessment.