氨烯己酸(Vigabatrin)是迄今为止最强的、副作用较少的GABA转氨酶的不可逆抑制剂。本品对复合型部分发作比强直型-阵挛性发作更有效,且耐受性良好。本文对本品进行开放性双盲试验,对比了两个不同剂量对耐药的复合型部分发作患者的效果。 75例严重癫痫患者,常规癫痫药物治疗后均不能控制发作,平均发作次数为每月11.5次。 Vigabatrin is by far the strongest, irreversible inhibitor of GABA aminotransferase with fewer side effects. The product of the composite partial seizures than tonic - clonic seizures more effective and well tolerated. This article on the open-label double-blind test, compared two different doses of drug-resistant composite partial seizures in patients with the effect. Seventy-five patients with severe epilepsy had no control of seizures after treatment with conventional epilepsy, with an average of 11.5 episodes per month.