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目的：探讨阿托伐他汀钙片治疗不稳定型心绞痛（UAP）的临床疗效。方法选取2013年1月—2015年1月伊犁哈萨克自治州新华医院心内科收治的 UAP 患者112例，按随机数字表法将其分为对照组与研究组，各56例。对照组患者予以常规治疗，研究组患者在对照组基础上加用阿托伐他汀钙片治疗。观察两组患者临床疗效、治疗前后心功能指标〔射血分数（EF）、每搏输出量（SV）、心输出量（CO）、舒张早期峰值流速/舒张晚期峰值流速（E/ A）〕、生理指标〔三酰甘油（TG）、总胆固醇（TC）、高敏 C 反应蛋白（ hs-CRP）、低密度脂蛋白-胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）〕及不良反应发生情况。结果研究组患者总有效率高于对照组，差异有统计学意义（P ﹤0.05）；治疗前两组患者 EF、SV、CO、E/ A 比较，差异无统计学意义（P ﹥0.05），治疗后研究组患者 EF、SV、CO 高于对照组，E/ A 低于对照组，差异有统计学意义（ P ﹤0.05）；治疗前两组患者 TG、TC、hs-CRP、LDL-C、HDL-C水平比较，差异无统计学意义（P ﹥0.05）；治疗后研究组患者 TG、TC、hs-CRP、LDL-C水平低于对照组，HDL-C水平高于对照组，差异有统计学意义（P ﹤0.05）；两组患者不良反应发生率比较，差异无统计学意义（P ﹥0.05）。结论阿托伐他汀钙片治疗 UAP 的临床疗效显著，可改善患者心功能及各项生理指标，且不良反应少。“,”Objective To explore the effect of atorvastatin in treating unstable angina pectoris(UAP). Methods A total of 112 patients with UAP were selected in Xinhua Hospital of Ili Kazak Autonomous Prefecture from January 2013 to Janu-ary 2015,according to the stochastic number table method,they were divided into control group and research group,56 cases in each group. Control group were given routine treatment,research group were given atorvastatin treatment on the basis of control group. Clinical effect,before and after treatment heart function index〔ejection fraction(EF),stroke volume(SV),cardiac output(CO),early diastolic velocity/ advanced diastolic velocity( E/ A)〕,physiological index〔 triglyceride( TG),total cholesterol(TC),high - sensitivity C - reactive protein(hs-CRP),low - density lipoprotein cholesterol(LDL-C),high -density lipoprotein cholesterol(HDL-C)〕and incidence of adverse reactions between the two groups were compared. Results The total effective rate of research group was higher than that of control group(P ﹤ 0. 05);before treatment,EF,SV,CO, E/ A showed no significant differences between the two groups(P ﹥ 0. 05),after treatmnet,EF,SV,CO of research group were higher than those of control group(P ﹤ 0. 05),E/ A of research group was lower than that of control group(P ﹤ 0. 05);before treatment,TG,TC,hs-CRP,LDL-C,HDL-C showed no significant differences between the two groups(P ﹥ 0. 05), after treatment,TG,TC,hs-CRP,LDL-C of research group were lower than those of control group(P ﹤ 0. 05),HDL-C of re-search group was higher than that control group(P ﹤ 0. 05);incidence of adverse reactions showed no significant differences be-tween the two groups(P ﹥ 0. 05). Conclusion Atorvastatin has notable curative effect in the treatment of UAP,can improve cardiac function and physiological index,has less adverse reactions.