目的:探讨慢性阻塞性肺病(COPD)急性加重期的治疗经验。方法:在抗生素控制感染的基础上,联合应用支气管扩张剂,糖皮质激素,观察临床疗效。结果:115例患者好转出院,19例患者病情加重死亡,因病情危重自动出院失访12例。结论:COPD急性加重期在控制感染基础上,同时扩张气道,降低气道高反应性,可明显缓解病情,可明显降低患者的病死率。 Objective: To explore the treatment experience of acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods: On the basis of antibiotics to control infection, the combination of bronchodilators and glucocorticoids was used to observe the clinical curative effect. Results: One hundred and fifteen patients were discharged after improvement. Nineteen patients were exacerbated and died of spontaneous discharge due to the critical condition. Twelve patients were discharged. Conclusion: In the acute exacerbation of COPD, on the basis of controlling the infection, it can expand the airway at the same time and reduce the airway hyperresponsiveness. It can relieve the disease obviously and reduce the mortality obviously.