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作者利用伤寒及肠炎沙门菌菌体脂多糖(LPS)作为抗原,建立了能检测沙门菌属感染所产生的血清特异性 IgM、IgG 及 IgA 的酶免疫测定(EIA)方法。实验检测的130例均为大便培养阳性病例。年龄1~76岁,儿童13例,成人117例。其中为鼠伤寒杆菌88例,肠炎沙门菌20例,其它沙门菌22例。除63例鼠伤寒杆菌感染病人标本,在起病后2.5个月采取外,其余标本均在感染后1~3周采集。对照组分两组:一组为来自同一地区100名健康献血员,另一组为非沙门菌引起的其它急性感染病例。
By using typhoid and Salmonella enteritidis lipopolysaccharide (LPS) as an antigen, the authors established an enzyme immunoassay (EIA) method capable of detecting serum-specific IgM, IgG and IgA produced by Salmonella infection. 130 cases of laboratory tests were stool culture positive cases. Ages 1 to 76 years old, 13 children, 117 adults. Among them, 88 were Salmonella typhimurium, 20 were Salmonella enteritidis and 22 were other Salmonella. In addition to 63 cases of Salmonella typhimurium infection in patients with specimens taken 2.5 months after onset, the remaining specimens were collected 1 to 3 weeks after infection. The control group consisted of two groups: one from 100 healthy blood donors from the same area and the other from non-Salmonella-causing other acute infections.