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目的探讨无创正压通气治疗老年肺癌重症呼吸衰竭患者的临床疗效。方法选取老年肺癌重症呼吸衰竭患者118例,随机分为观察组与对照组,每组各59例。对照组给予有创呼吸支持,观察组予以无创正压通气。比较两组治疗前、治疗24h后的血气指标,治疗前、脱机时的呼吸频率(R)、心率(HR),治疗14d后进行临床疗效判定。结果治疗24h后两组PaCO2、PaO2,脱机时R及HR,以及总有效率比较,差异均无统计学意义,P>0.05。观察组组ICU住院时间、并发症率均少于或低于对照组,P<0.05。结论无创正压通气、有创呼吸支持治疗老年肺癌重症呼吸衰竭患者具有相似的临床疗效,但无创正压通气减少了ICU住院时间,降低了并发症发生率,对于老年肺癌重症呼吸衰竭患者的临床治疗具有一定的借鉴意义。
Objective To investigate the clinical efficacy of non-invasive positive pressure ventilation in the treatment of elderly patients with severe respiratory failure. Methods 118 elderly patients with severe respiratory failure of lung cancer were randomly divided into observation group and control group, 59 cases in each group. The control group was given invasive respiratory support, the observation group was non-invasive positive pressure ventilation. The blood gas indexes before treatment, 24h after treatment, respiratory rate (R) and heart rate (HR) before treatment and after treatment were compared between two groups for clinical efficacy judgment. Results There was no significant difference in PaCO2, PaO2, R and HR, and total effective rate between two groups after treatment for 24 h, P> 0.05. The ICU stay and complication rates in the observation group were both less than or less than those in the control group, P <0.05. Conclusion Noninvasive positive pressure ventilation and invasive respiratory support have similar clinical efficacy in elderly patients with severe respiratory failure in elderly patients with lung cancer. However, noninvasive positive pressure ventilation reduces the length of hospital stay and the incidence of complications in elderly patients with severe respiratory failure in elderly patients with lung cancer Treatment has a certain reference value.