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目的探讨男性阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的红细胞计数及红细胞平均体积、红细胞平均压积的改变与其病情严重程度的关系,及OSAHS与心脑血管疾病的关系。方法对90例男性OSAHS患者整夜多导睡眠图进行分析,按照OSAHS分级标准:AHI5～20为轻度;AHI21～40为中度;AHI>41为重度分组,对各组OSAHS患者及对照组患者的红细胞计数及红细胞平均体积、红细胞平均压积进行检测。结果轻度OSAHS组患者红细胞计数及红细胞平均体积、红细胞平均压积与对照组均无明显差异;中度OSAHS组的患者红细胞计数、红细胞平均压积高于对照组;重度OSAHS组患者红细胞计数及红细胞压积均明显高于对照组,中度OSAHS组与重度OSAHS组患者红细胞计数及红细胞压积差异无统计学意义,两者与AHI呈正相关(r=0.353;0.248)。结论 OSAHS患者的红细胞计数及红细胞压积升高,与OSAHS的严重程度呈正相关。OSAHS是心脑血管疾病的危险因素。
Objective To investigate the relationship between the changes of erythrocyte count and the average volume of red blood cells, the change of erythrocyte mean pressure, and the severity of the disease in male patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) and the relationship between OSAHS and cardiovascular and cerebrovascular diseases. Methods According to the OSAHS grading criteria, 90 OSAHS patients were analyzed with OSAHS. AHI5 ~ 20 was mild; AHI21 ~ 40 was moderate; AHI> 41 was severe. OSAHS patients in each group and control group The patient’s red blood cell count and the average volume of red blood cells, erythrocyte mean pressure test. Results There was no significant difference in erythrocyte count, erythrocyte mean volume and erythrocyte mean pressure in mild OSAHS patients compared with the control group. The patients with moderate OSAHS had higher red blood cell count and red blood cell mean pressure than those in the control group. The hematocrit was significantly higher than that of the control group. There was no significant difference of erythrocyte count and hematocrit between the moderate OSAHS group and the severe OSAHS group. Both of them had a positive correlation with AHI (r = 0.353; 0.248). Conclusion The red blood cell count and hematocrit in OSAHS patients are positively correlated with the severity of OSAHS. OSAHS is a risk factor for cardiovascular and cerebrovascular diseases.