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CK(或称 CPK)可逆地催化磷酸肌酸的合成,对身体的能量代谢,特别是对肌肉的收缩起重要作用。1934年由 Lohmann 在肌肉中发现,故也称 Lohmann 化酶。CK 主要分布在骨骼肌、心肌、脑及平滑肌等部位,红细胞及其他脏器如肺和肝等,几乎不含有。释放到血中的 CK 是由于含 CK 多的脏器受损伤或细胞膜通透性增强所致。Ebashi 等在1959年、Dreifus 等在1960年分别报告了进行性肌萎缩症和急性心肌梗
CK (or CPK) reversibly catalyzes the synthesis of creatine phosphate, which plays an important role in the body’s energy metabolism, especially muscle contraction. In 1934 by Lohmann found in muscle, it is also called Lohmann enzyme. CK is mainly distributed in skeletal muscle, myocardium, brain and smooth muscle and other parts of the red blood cells and other organs such as lungs and liver, almost does not contain. CK released into the blood is due to more CK-containing organs damaged or increased permeability of the cell membrane. Ebashi et al in 1959, Dreifus et al reported in 1960 were progressive muscular dystrophy and acute myocardial infarction