论文部分内容阅读
高脂血症的患者血中EPA和DHA含量,EPA/AA和DHA/EPA值均低于健康对照组。以淡水鱼油乳化剂对44例高血脂症病人作小剂量的n-3不饱和脂肪酸的补充(EPA+DHA约1.59g/d),3～4w后,患者血浆中EPA和DHA分别增加了242%(P<0.01)和1018％(P<0.01),EPA/AA和DHA/EPA值亦显著提高;血浆TC、TG、LDL及Lp(a)分别降低19.6％(P<0.01)、23.9%(P<0.01)、24.2％(P<0.01)和22.3%(P<0.05),apoA,升高为10.1％(P<0.05)。观察结果提示,淡水鱼油有利于高脂血症和冠心病的防治。
The levels of EPA and DHA, EPA / AA and DHA / EPA in patients with hyperlipidemia were lower than those in healthy controls. 44 patients with hyperlipidemia were supplemented with low dose of n-3 unsaturated fatty acid (EPA + DHA about 1.59g / d) with freshwater fish oil emulsifier. After 3 ~ 4w, the plasma EPA and DHA increased by 242 (P <0.01) and 1018% (P <0.01). The levels of EPA / AA and DHA / EPA also increased significantly. The levels of TC, TG, LDL and Lp (a) decreased by 19.6% (P <0.01), 24.2% (P <0.01) and 22.3% (P <0.05) respectively. The apoA level increased to 10.1% (P <0.05). Observations suggest that freshwater fish oil is beneficial to the prevention and treatment of hyperlipidemia and coronary heart disease.