降钙素基因相关肽(CGRP)广泛分布在中枢和周围神经系统,与感觉信息,特别是伤害性刺激信息的传人与整合关系密切。本文仅对脊髓背角及背根神经节(DRG)的CGRP与神经病理性疼痛的关系,包括神经病理性疼痛状态下脊髓背角DRG内CGRP水平的变化、抑制CGRP生成/作用对疼痛程度的影响等作一综述。 Calcitonin gene-related peptide (CGRP) is widely distributed in the central and peripheral nervous system, and sensory information, especially harmful to the stimulation of information transmission and integration are closely related. In this paper, we only study the relationship between CGRP and neuropathic pain in dorsal horn of spinal cord and dorsal root ganglion (DRG), including changes of CGRP level in DRG of spinal dorsal horn in spinal cord under neuropathic pain, and the effect of inhibiting the formation / Make a review