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目的:探讨美托洛尔治疗高海拔地区慢性充血性心力衰竭的临床疗效。方法:将56例心功能Ⅱ~Ⅲ级的慢性心力衰竭患者,随机分为治疗组和对照组。在常规治疗的基础上,治疗组加用美托洛尔。观察治疗组临床症状、心率及超声心动图指标改善情况。结果:治疗组总有效率高于对照组(P<0.05);治疗组超声心动图指标改善、心功能较对照组提高(P<0.01)。结论:β-受体阻滞剂治疗高海拔地区慢性充血性心力衰竭可改善心功能和临床症状。
Objective: To investigate the clinical efficacy of metoprolol in the treatment of chronic congestive heart failure at high altitude. Methods: Fifty-six patients with chronic heart failure with grade Ⅱ ~ Ⅲ heart function were randomly divided into treatment group and control group. On the basis of conventional treatment, the treatment group plus metoprolol. Observed the treatment group clinical symptoms, heart rate and echocardiographic parameters to improve the situation. Results: The total effective rate of the treatment group was higher than that of the control group (P <0.05). The echocardiographic parameters of the treatment group were improved and the cardiac function was improved compared with the control group (P <0.01). CONCLUSIONS: β-blockers improve heart function and clinical symptoms in patients with chronic congestive heart failure at high altitudes.